SCHEMBL654293

SCHEMBL654293

Cc1cccc(OCC(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.69
FFAR1 O14842 2/20 0.65
KMT2A Q03164 4/20 0.62
GAA P10253 3/20 0.62
ALOX15 P16050 1/20 0.62
MAPK1 P28482 3/20 0.60
MAPT P10636 2/20 0.60
HTT P42858 2/20 0.60
POLB P06746 1/20 0.60
MEN1 O00255 3/20 0.58
PTPN7 P35236 1/20 0.56
ALDH1A1 P00352 1/20 0.56
PLA2G1B P04054 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ATG4B Q9Y4P1 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30024728 1.00 LMNA (0.69) LMNAFFAR1KMT2AGAAALOX15
SCHEMBL413254 0.86 LMNA (0.81) LMNAFFAR1KMT2AALOX15MAPK1
SCHEMBL11128406 0.85 KMT2A (0.62) LMNAKMT2AGAAMAPK1MAPT
SCHEMBL8976610 0.85 KMT2A (0.62) LMNAKMT2AGAAMAPK1MAPT
SCHEMBL2719604 0.84 KMT2A (0.60) LMNAKMT2AGAAMAPK1MAPT
SCHEMBL5532773 0.84 KMT2A (0.60) LMNAKMT2AGAAMAPK1MAPT
SCHEMBL8948941 0.83 KMT2A (0.61) LMNAKMT2AGAAMAPK1MAPT
SCHEMBL9320123 0.82 KMT2A (0.59) LMNAKMT2AGAAMAPK1MAPT
SCHEMBL9911067 0.82 GAA (0.72) LMNAKMT2AGAAMAPK1MAPT
SCHEMBL2777259 0.82 L3MBTL1 (0.64) LMNAKMT2AGAAMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745457-A High-adaptability concrete superplasticizer, preparation method and application thereof 南京博特新材料有限公司 2023-03-07 CN claimed
CN-115725035-A Slump-retaining concrete superplasticizer, preparation method and application thereof 博特新材料泰州有限公司 2023-03-03 CN claimed
CN-105237561-A Di-n-butyltin m-methyl phenoxy acetic ester and preparation method and application thereof UNIV HENGYANG NORMAL 2016-01-13 CN claimed
CN-102516196-A Alpha, beta-unsaturated ketone compound containing thiazole heterocycle, its preparation method and application UNIV SHANDONG 2012-06-27 CN claimed
EP-3704094-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-11 EP disclosed
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2025-04-17 US disclosed
US-20250115563-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC 2025-04-10 US disclosed
US-20240166652-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ABBVIE INC. 2024-05-23 US disclosed
EP-4356971-A2 MODULATORS OF THE INTEGRATED STRESS PATHWAY Calico Life Sciences LLC (US) 2024-04-24 EP disclosed
EP-3697421-B1 LONGER-ACTING PROGESTIN PRODRUG CONTRACEPTIVES EVESTRA INC (US) 2024-04-17 EP disclosed
CN-117843968-A Multifunctional solid concrete superplasticizer, preparation method and application 江苏苏博特新材料股份有限公司 2024-04-09 CN disclosed
EP-3704098-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2024-01-24 EP disclosed
US-4598087-A DIURETICS; ANALGESICS, PSYCHOTHERAPEUTICS WARNER-LAMBERT COMPANY (US) 1986-07-01 US disclosed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP disclosed
EP-0146297-A1 Substituted trans-1,2-diaminocyclohexyl amide compounds WARNER-LAMBERT COMPANY (US) 1985-06-26 EP disclosed
EP-0104483-A2 Sulfamoyl benzophenon derivatives, process for their preparation, their use, and pharmaceutical compositions based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1984-04-04 EP disclosed
US-4415494-A BLUE-TO-BLACK COLORFAST DISPERSE, NITRO DYES; DIAZOTIZING A P-NITROANILINE AND COUPLING WITH AN N-SUBSTITUTED 1-NAPHTHYLAMINE CASSELLA AKTIENGESELLSCHAFT (DE) 1983-11-15 US disclosed
US-4314845-A N4 -Phenoxyalkanoylsulfanilamides and herbicidal composition containing the same SHIONOGI & CO., LTD. (JP) 1982-02-09 US disclosed
EP-0036545-A1 Water insoluble monoazo dyes, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1981-09-30 EP disclosed
US-3985559-A Toner powder for electrostatic images OCE-VAN DER GRINTEN N.V. (NL) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 LMNA 3376/4885FFAR1 1632/4885KMT2A 4320/4885
US-20240166652-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 LMNA 3376/4885FFAR1 1632/4885KMT2A 4320/4885
US-20250115563-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 LMNA 3376/4885FFAR1 1632/4885KMT2A 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.