SCHEMBL8949329

SCHEMBL8949329

O=C1CC=Cc2nc3ccccc3cc21.O=C1c2ccccc2C(=O)c2c1cc(Br)c(Cl)c2Cl

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
PGAM1 P18669 2/20 0.30
PTPN1 P18031 1/20 0.30
PKLR P30613 1/20 0.30
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8949073 0.85 RAB9A (0.43) NPC1RAB9A
Anthraquinone SCHEMBL2778406 0.84 NPC1 (0.54) NPC1RAB9A
Anthraquinone SCHEMBL11078992 0.84 NPC1 (0.54) NPC1RAB9A
SCHEMBL19291 0.79 NPC1 (0.44) NPC1RAB9A
SCHEMBL11519732 0.79 NPC1 (0.44) NPC1RAB9A
SCHEMBL6890133 0.78 NPC1 (0.42) NPC1RAB9A
Methane SCHEMBL11523432 0.78 NPC1 (0.42) NPC1RAB9A
Hydrochloric Acid SCHEMBL27346450 0.78 NPC1 (0.42) NPC1RAB9A
SCHEMBL4674985 0.77 NPC1 (0.41) NPC1RAB9A
SCHEMBL27707876 0.76 NPC1 (0.50) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525743-A Preparation of anthraquinone imide compounds BASF AKTIENGESELLSCHAFT (DE) 1996-06-11 US disclosed