Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 10/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899777 | 0.82 | CASP1 (1.00) | CASP1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8949196 | 0.80 | CASP1 (0.77) | CASP1ALDH1A1HPGDCYP2C9HSD17B10 | |
| SCHEMBL7275356 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL7276252 | 0.76 | HPGD (0.57) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL30051126 | 0.74 | CASP1 (0.62) | CASP1KDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL140932 | 0.74 | CASP1 (0.62) | CASP1KDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL7992182 | 0.73 | CYP4F2 (0.48) | KDM4EALDH1A1GAASMN1; SMN2NPSR1 | |
| SCHEMBL27944765 | 0.73 | CYP4F2 (0.58) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL2650679 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL8949195 | 0.73 | SMN1; SMN2 (0.59) | KDM4EALDH1A1HPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |