Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949032 | 0.91 | RXFP1 (0.37) | PHGDHITGB3ITGA2BRXFP1HPGD | |
| SCHEMBL8949398 | 0.85 | ITGB3 (0.40) | PHGDHITGB3ITGA2BF2KLKB1 | |
| SCHEMBL8949239 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL8949379 | 0.82 | HPGD (0.38) | PHGDHITGB3ITGA2BHPGDKLKB1 | |
| SCHEMBL8949063 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL8949221 | 0.80 | HPGD (0.37) | PHGDHITGB3ITGA2BHPGD | |
| SCHEMBL8949033 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8949233 | 0.79 | HPGD (0.40) | PHGDHITGB3ITGA2BHPGDF2 | |
| SCHEMBL8949188 | 0.79 | ALDH1A1 (0.38) | PHGDHITGB3ITGA2BHPGDF2 | |
| Hydrochloric Acid SCHEMBL8949365 | 0.79 | F2 (0.39) | ITGB3ITGA2BRXFP1HPGDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |