Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.43 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949328 | 0.94 | ITGB3 (0.47) | ITGB3ITGA2BSCDNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8949331 | 0.89 | NPC1 (0.41) | ITGB3ITGA2BSCDNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8949350 | 0.83 | NPC1 (0.42) | ITGB3ITGA2BSCDNPC1RAB9A | |
| SCHEMBL8949016 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BSCDNPC1RAB9A | |
| SCHEMBL8949403 | 0.77 | ITGB3 (0.48) | ITGB3ITGA2BSCDNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8949079 | 0.76 | NPC1 (0.41) | ITGB3ITGA2BSCDNPC1RAB9A | |
| SCHEMBL8949275 | 0.75 | ITGB3 (0.46) | ITGB3ITGA2BSCDNPC1RAB9A | |
| SCHEMBL8949376 | 0.74 | ITGB3 (0.51) | ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL8949313 | 0.72 | ITGB3 (0.53) | ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL8949037 | 0.72 | NPC1 (0.41) | SCDNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |