Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949067 | 0.88 | ITGB3 (0.40) | SMN1; SMN2ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8949209 | 0.81 | ITGB3 (0.56) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949325 | 0.76 | ITGB3 (0.45) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8949272 | 0.76 | ITGB3 (0.48) | ITGB3ITGA2BTSHR | |
| SCHEMBL9278118 | 0.75 | ITGB3 (0.37) | SMN1; SMN2ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8949046 | 0.74 | ITGB3 (0.50) | ITGB3ITGA2BPOLBTSHRKMT2A | |
| SCHEMBL8949143 | 0.73 | ITGB3 (0.45) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949247 | 0.72 | KDM1A (0.44) | ITGB3ITGA2BHPGD | |
| SCHEMBL8949071 | 0.71 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL8949254 | 0.71 | ITGB3 (0.39) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |