Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949113 | 0.91 | TMPRSS15 (0.41) | PRSS1TMPRSS15CNR1CNR2MAPK14 | |
| SCHEMBL8949147 | 0.90 | PRSS1 (0.37) | PRSS1TMPRSS15CNR1CNR2MAPK14 | |
| SCHEMBL8949277 | 0.86 | CNR2 (0.46) | PRSS1CNR1CNR2ITGB3ITGA2B | |
| SCHEMBL8949148 | 0.86 | CNR2 (0.46) | PRSS1CNR1CNR2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949314 | 0.81 | F2 (0.36) | PRSS1TMPRSS15CNR2MAPK14F2 | |
| SCHEMBL8949034 | 0.78 | CFTR (0.42) | PRSS1TMPRSS15CNR1CNR2F2 | |
| SCHEMBL8949131 | 0.78 | CFTR (0.42) | PRSS1TMPRSS15CNR1CNR2F2 | |
| SCHEMBL8949399 | 0.75 | CNR2 (0.49) | PRSS1CNR1CNR2ITGB3ITGA2B | |
| SCHEMBL8949269 | 0.74 | EGLN1 (0.47) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL8949029 | 0.73 | CNR2 (0.49) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |