Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.43 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949195 | 0.86 | SMN1; SMN2 (0.59) | MEN1KMT2ASMN1; SMN2TDP1POLB | |
| Benzyl Bromide SCHEMBL9263877 | 0.82 | SMN1; SMN2 (0.54) | MEN1KMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL7723670 | 0.81 | MAPT (0.63) | MEN1KMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL8949362 | 0.81 | CNR2 (0.61) | CNR1CNR2SMN1; SMN2CHRM4 | |
| SCHEMBL8949327 | 0.78 | CNR2 (0.60) | CNR1CNR2MEN1KMT2ACHRM4 | |
| SCHEMBL7275259 | 0.78 | PHGDH (0.48) | MEN1KMT2AGAACASP1 | |
| SCHEMBL1925446 | 0.77 | CNR2 (0.49) | CNR1CNR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27538726 | 0.76 | CNR2 (0.46) | CNR1CNR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8949200 | 0.76 | TSHR (0.46) | MEN1KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL7724840 | 0.73 | MAPT (0.61) | KMT2ASMN1; SMN2TDP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |