Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.60 |
| ▸ | CNR1 | P21554 | 4/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | BRD1 | O95696 | 1/20 | 0.41 |
| ▸ | CCL2 | P13500 | 1/20 | 0.41 |
| ▸ | TAF1 | P21675 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949362 | 0.92 | CNR2 (0.61) | CNR2CNR1CHRM4BRD4PRKAA2 | |
| Hydrochloric Acid SCHEMBL8949172 | 0.88 | CNR2 (0.63) | CNR2CNR1BRD4KMT2ACRHR1 | |
| SCHEMBL8949357 | 0.86 | CNR2 (0.59) | CNR2CNR1BRD4MEN1KMT2A | |
| SCHEMBL8949262 | 0.84 | EGLN1 (0.45) | CNR2CNR1MEN1RAB9AKMT2A | |
| SCHEMBL8949141 | 0.84 | EGLN1 (0.45) | CNR2CNR1MEN1RAB9AKMT2A | |
| SCHEMBL8949256 | 0.84 | EGLN1 (0.45) | CNR2CNR1MEN1RAB9AKMT2A | |
| SCHEMBL9260471 | 0.82 | CNR2 (0.41) | CNR2CNR1 | |
| SCHEMBL8949106 | 0.79 | CNR2 (0.56) | CNR2CNR1BRD4MEN1RAB9A | |
| Hydrochloric Acid SCHEMBL8949076 | 0.79 | CNR2 (0.64) | CNR2CNR1BRD4CRHR1CRHR2 | |
| SCHEMBL8949294 | 0.78 | CNR1 (0.46) | CNR2CNR1CHRM4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |