SCHEMBL8949303

SCHEMBL8949303

O=S(=O)(O)c1ccccc1-c1ccccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
PGAM1 P18669 1/20 0.40
BCAT2 O15382 1/20 0.39
AKR1B1 P15121 1/20 0.39
MYC P01106 1/20 0.39
MEN1 O00255 2/20 0.38
APAF1 O14727 2/20 0.38
NPC1 O15118 2/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL27503675 0.98 PTGS2 (0.46) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
SCHEMBL29743050 0.91 CASP1 (0.47) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
SCHEMBL232659 0.91 CASP1 (0.47) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
Water SCHEMBL27371066 0.89 CASP1 (0.46) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
SCHEMBL28934633 0.89 CASP1 (0.46) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
Lithium SCHEMBL3173875 0.89 CASP1 (0.46) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
SCHEMBL1870052 0.89 CASP1 (0.46) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
SCHEMBL29194067 0.89 CASP1 (0.46) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
Hydrochloric Acid SCHEMBL11757790 0.89 CASP1 (0.46) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1
Biphenyl SCHEMBL1706263 0.88 CASP1 (0.45) PTGS2SMN1; SMN2TSHRCASP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4565546-A Condensation product and use thereof as dispersant for pitch in water slurry NIKKA CHEMICAL INDUSTRY CO. (JP) 1986-01-21 US claimed
US-4245996-A Condensation products of terphenylsulphonic acids, naphthalenesulphonic acids, bis-(4-hydroxyphenyl) sulphone and formaldehyde BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US claimed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US claimed
US-5508389-A CARRYING OUT DIAZOTIZATION OR COUPLING IN THE PRESENCE OF AN AUXILLIARY SUCH AS A NAPHTHALENESULFONIC ACID-FORMALDEHYDE CONDENSATION PRODUCT WHICH EXERTS A VISCOSITY-REDUCING EFFECT ON PASTY PHASES HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
US-5352241-A Process for retanning mineral tanned leathers with aromatic sulphonic acids BAYER AKTIENGESELLSCHAFT (DE) 1994-10-04 US disclosed
US-5279622-A Triazine dyes BAYER AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
US-4754020-A ACID IS ION EXCHANGE RESIN, EASY SEPARATION BAYER AKTIENGESELLSCHAFT (DE) 1988-06-28 US disclosed
US-4711642-A Liquid, water containing mono-fluoro-triazinyl reactive dyestuff preparation with pH 8-12 BAYER AKTIENGESELLSCHAFT (DE) 1987-12-08 US disclosed
US-4702744-A REPLACING SODIUM IONS WITH LITHIUM AND/OR AMMONIUM IONS BAYER AKTIENGESELLSCHAFT (DE) 1987-10-27 US disclosed
US-4685933-A Concentrated reactive dyestuff solutions containing cyanamide compound as stabilizer BAYER AKTIENGESELLSCHAFT (DE) 1987-08-11 US disclosed
US-4602915-A Storage-stable solution of a copper phthalocyanine reactive dyestuff BAYER AKTIENGESELLSCHAFT (DE) 1986-07-29 US disclosed
US-4565546-A Condensation product and use thereof as dispersant for pitch in water slurry NIKKA CHEMICAL INDUSTRY CO. (JP) 1986-01-21 US disclosed
US-4318848-A Process for the neutralization of basic reaction compositions BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4245996-A Condensation products of terphenylsulphonic acids, naphthalenesulphonic acids, bis-(4-hydroxyphenyl) sulphone and formaldehyde BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4245996-A Condensation products of terphenylsulphonic acids, naphthalenesulphonic acids, bis-(4-hydroxyphenyl) sulphone and formaldehyde BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4245996-A Condensation products of terphenylsulphonic acids, naphthalenesulphonic acids, bis-(4-hydroxyphenyl) sulphone and formaldehyde BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0008032-A1 Condensation products from terphenyl-sulphonic acids, naphthalene-sulphonic acids, bis-(4-hydroxyphenyl)-sulphone and formaldehyde, and their use as tanning agents BAYER AG (DE) 1980-02-20 EP disclosed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-3906037-A Formaldehyde condensation products of terphenyl-sulphonic acids BAYER AG 1975-09-16 US disclosed
US-3906037-A Formaldehyde condensation products of terphenyl-sulphonic acids BAYER AG 1975-09-16 US disclosed