Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949256 | 1.00 | EGLN1 (0.45) | EGLN1CFTRCNR2CNR1CHEK1 | |
| SCHEMBL8949141 | 1.00 | EGLN1 (0.45) | EGLN1CFTRCNR2CNR1CHEK1 | |
| SCHEMBL8949269 | 0.90 | EGLN1 (0.47) | EGLN1CNR2CNR1KLK7PHGDH | |
| SCHEMBL8949327 | 0.84 | CNR2 (0.60) | CNR2CNR1KLK7MEN1RAB9A | |
| SCHEMBL8949131 | 0.84 | CFTR (0.42) | CFTRCNR2CNR1KLK7 | |
| Hydrochloric Acid SCHEMBL8949162 | 0.84 | CNR2 (0.46) | CFTRCNR2CNR1KLK7MEN1 | |
| SCHEMBL8949034 | 0.84 | CFTR (0.42) | CFTRCNR2CNR1KLK7 | |
| SCHEMBL8949258 | 0.83 | CNR2 (0.41) | CFTRCNR2CNR1KLK7MEN1 | |
| SCHEMBL8949056 | 0.83 | CNR2 (0.41) | CFTRCNR2CNR1KLK7MEN1 | |
| SCHEMBL9260471 | 0.81 | CNR2 (0.41) | EGLN1CFTRCNR2CNR1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |