Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 8/20 | 0.68 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | VEGFA | P15692 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475754 | 0.88 | QPCT (0.67) | QPCTSMN1; SMN2VEGFAEGLN1TBXAS1 | |
| SCHEMBL3181153 | 0.87 | SMN1; SMN2 (0.57) | QPCTSMN1; SMN2VEGFAEGLN1TBXAS1 | |
| SCHEMBL14416015 | 0.85 | MEN1 (0.61) | QPCT | |
| SCHEMBL14416010 | 0.81 | SMN1; SMN2 (0.56) | QPCTSMN1; SMN2VEGFAEGLN1TBXAS1 | |
| SCHEMBL14416017 | 0.81 | CYP19A1 (0.60) | QPCTSMN1; SMN2VEGFAEGLN1AKT1 | |
| Hydrochloric Acid SCHEMBL8949368 | 0.81 | NOS1 (0.48) | CACNA1BQPCTSMN1; SMN2 | |
| SCHEMBL8443968 | 0.80 | HMOX1 (0.65) | QPCTSMN1; SMN2VEGFAEGLN1 | |
| SCHEMBL14416009 | 0.80 | CYP19A1 (0.67) | CACNA1BQPCTSMN1; SMN2 | |
| SCHEMBL6571544 | 0.80 | CYP1A2 (0.61) | QPCTSMN1; SMN2 | |
| SCHEMBL6638645 | 0.80 | QPCT (0.59) | QPCTSMN1; SMN2VEGFAEGLN1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | claimed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1995022327-A1 | USE OF 1-(ARYLALKYLAMINOALKYL) IMIDAZOLES FOR TREATING NEUROLOGICAL DAMAGE | KNOLL AG (DE) | 1995-08-24 | — | — | WO | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |