Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | QPCT | Q16769 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949432 | 0.99 | ALDH1A1 (0.55) | ALDH1A1QPCTKMT2APRKCIMEN1 | |
| SCHEMBL8443962 | 0.88 | LMNA (0.56) | ALDH1A1QPCTKMT2AMEN1POLB | |
| SCHEMBL7879569 | 0.88 | QPCT (0.49) | ALDH1A1QPCTKMT2APRKCIMEN1 | |
| SCHEMBL13696720 | 0.88 | CYP11B1 (0.55) | ALDH1A1QPCTPRKCISMN1; SMN2CYP19A1 | |
| Hydrochloric Acid SCHEMBL2887150 | 0.87 | LMNA (0.55) | ALDH1A1QPCTKMT2AMEN1POLB | |
| SCHEMBL8444382 | 0.86 | GSK3A (0.48) | ALDH1A1QPCTKMT2AMEN1POLB | |
| SCHEMBL7873790 | 0.85 | QPCT (0.46) | ALDH1A1QPCTKMT2APRKCIMEN1 | |
| Hydrochloric Acid SCHEMBL8445872 | 0.85 | ALDH1A1 (0.47) | ALDH1A1QPCTKMT2AMEN1POLB | |
| SCHEMBL8444094 | 0.84 | TP53 (0.52) | ALDH1A1QPCTKMT2APRKCIMEN1 | |
| SCHEMBL8949312 | 0.84 | LMNA (0.48) | ALDH1A1QPCTKMT2APRKCIMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | claimed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |