Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446130 | 0.86 | ADAMTS4 (0.35) | SMN1; SMN2 | |
| SCHEMBL8443913 | 0.80 | SMN1; SMN2 (0.34) | NPSR1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL8443190 | 0.77 | CYP17A1 (0.40) | NPSR1 | |
| Hydrochloric Acid SCHEMBL8949238 | 0.76 | CYP17A1 (0.39) | NPSR1 | |
| SCHEMBL8443445 | 0.75 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9367627 | 0.72 | TAAR1 (0.45) | NPSR1L3MBTL1 | |
| SCHEMBL13975752 | 0.69 | SMN1; SMN2 (0.54) | NPSR1POLBSMN1; SMN2L3MBTL1CNR1 | |
| SCHEMBL7034295 | 0.69 | KCNH2 (0.36) | — | |
| SCHEMBL8446034 | 0.69 | KMT2A (0.33) | NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9595179 | 0.68 | BRS3 (0.38) | NPSR1POLBSMN1; SMN2L3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | claimed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |