Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957175 | 0.85 | LTB4R (0.61) | LTB4RPPARAPPARGLMNASMN1; SMN2 | |
| SCHEMBL8949549 | 0.82 | ABCB1 (0.49) | USP2LTB4RPPARAPPARGABCB1 | |
| SCHEMBL8949613 | 0.81 | LTB4R (0.51) | LTB4RALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL8580824 | 0.80 | LTB4R (0.52) | LTB4RSMN1; SMN2PTPN1TDP1L3MBTL1 | |
| SCHEMBL8949624 | 0.78 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL2010417 | 0.75 | USP2 (0.67) | USP2ABCB1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2871402 | 0.75 | PPARD (0.58) | USP2PPARAPPARGABCB1ALDH1A1 | |
| SCHEMBL14252838 | 0.74 | USP2 (0.57) | USP2ABCB1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30717645 | 0.73 | USP2 (0.61) | USP2ABCB1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10687745 | 0.73 | CYSLTR2 (0.62) | LTB4RPPARAPPARGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |