Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957184 | 0.84 | LTB4R (0.58) | PPARGPPARAALDH1A1LMNAMAPT | |
| SCHEMBL14252837 | 0.83 | USP2 (0.55) | ABCB1USP2ESR1CASP3CASP7 | |
| SCHEMBL6561740 | 0.82 | LTB4R (0.46) | PTPN1CNR1CNR2LTB4RCTSD | |
| SCHEMBL8949587 | 0.82 | USP2 (0.49) | ABCB1USP2PPARGPPARACASP3 | |
| SCHEMBL3154126 | 0.82 | L3MBTL1 (0.62) | ABCB1USP2ESR1CASP3CASP7 | |
| SCHEMBL14252840 | 0.81 | USP2 (0.52) | ABCB1USP2ESR1CASP3CASP7 | |
| SCHEMBL6559825 | 0.80 | ALDH1A1 (0.49) | ALDH1A1CNR1CNR2LTB4RCTSD | |
| SCHEMBL14252838 | 0.80 | USP2 (0.57) | ABCB1USP2ESR1CASP3CASP7 | |
| SCHEMBL27545957 | 0.80 | CNR1 (0.56) | PTPN1ALDH1A1HPGDCA12CA1 | |
| SCHEMBL6561729 | 0.79 | L3MBTL1 (0.51) | NPC1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |