Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 12/20 | 0.80 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 3/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949594 | 0.89 | LTB4R (1.00) | LTB4RLTB4R2PDE5A | |
| SCHEMBL8949771 | 0.89 | LTB4R (0.82) | LTB4RLTB4R2 | |
| SCHEMBL8949589 | 0.88 | LTB4R (0.77) | LTB4RLTB4R2PDE5A | |
| SCHEMBL8949715 | 0.87 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL8949580 | 0.86 | LTB4R (0.82) | LTB4RLTB4R2 | |
| SCHEMBL8949619 | 0.85 | LTB4R (0.78) | LTB4RLTB4R2 | |
| SCHEMBL8949612 | 0.84 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL8949773 | 0.80 | LTB4R (0.79) | LTB4RLTB4R2PDE5A | |
| SCHEMBL8949720 | 0.80 | LTB4R (1.00) | LTB4RLTB4R2PDE5A | |
| SCHEMBL8949716 | 0.79 | LTB4R (0.81) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |