Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 15/20 | 0.82 |
| ▸ | LTB4R2 | Q9NPC1 | 10/20 | 0.82 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949716 | 0.92 | LTB4R (0.81) | LTB4RLTB4R2GRM2PPARDPPARG | |
| SCHEMBL8949687 | 0.91 | LTB4R (0.82) | LTB4RLTB4R2GRM2PPARDPPARG | |
| SCHEMBL8949774 | 0.90 | LTB4R (1.00) | LTB4RLTB4R2PPARDPPARG | |
| SCHEMBL8949599 | 0.89 | LTB4R (0.79) | LTB4RLTB4R2PPARDPPARG | |
| SCHEMBL8949588 | 0.89 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL8949701 | 0.83 | LTB4R (0.80) | LTB4RLTB4R2PPARDPPARG | |
| SCHEMBL8949721 | 0.83 | LTB4R (1.00) | LTB4RLTB4R2PPARDPPARG | |
| SCHEMBL8949619 | 0.80 | LTB4R (0.78) | LTB4RLTB4R2GRM2PPARD | |
| SCHEMBL8949612 | 0.79 | LTB4R (0.80) | LTB4RLTB4R2GRM2PPARD | |
| SCHEMBL8949715 | 0.78 | LTB4R (0.80) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |