⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974861 | 0.84 | — | — | |
| SCHEMBL9054241 | 0.81 | — | — | |
| SCHEMBL6257072 | 0.80 | PTPN7 (0.41) | — | |
| SCHEMBL8045294 | 0.80 | PTPN7 (0.41) | — | |
| SCHEMBL5339877 | 0.80 | PTPN7 (0.41) | — | |
| SCHEMBL9861704 | 0.76 | — | — | |
| SCHEMBL8663105 | 0.76 | — | — | |
| SCHEMBL580294 | 0.76 | TDP1 (0.45) | — | |
| SCHEMBL27703598 | 0.75 | KMT2A (0.56) | — | |
| SCHEMBL619312 | 0.75 | TDP1 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558980-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C N C C S S C A R L COLLEZIONE NAZ DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2021-01-27 | — | — | EP | claimed |
| US-10815222-B2 | Compounds for use in the treatment of kinetoplastid infection | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2020-10-27 | — | — | US | claimed |
| US-20200095232-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2020-03-26 | — | — | US | claimed |
| EP-3558980-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening (IT) | 2019-10-30 | — | — | EP | claimed |
| WO-2018115275-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | IRBM SCIENCE PARK S.P.A. (IT) | 2018-06-28 | — | — | WO | claimed |
| CN-1123547-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | UNIV NEW YORK STATE RES FOUND (US) | 1996-05-29 | — | — | CN | claimed |
| US-5480761-A | CHROMOGENIC PHOTOGRAPHIC ELEMENTS WITH DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| US-5445913-A | Mixing spectrally dye-sensitized silver halide emulsion melt and dry diffusion transfer facilitating thermal solvent; coating substrate | EASTMAN KODAK COMPANY (US) | 1995-08-29 | — | — | US | claimed |
| WO-2024146512-A1 | TRI-SUBSTITUTED PHENYL CYCLOHEXENE THIOETHER COMPOUND AND USE THEREOF | 沈阳万菱生物技术有限公司 | 2024-07-11 | — | — | WO | disclosed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| CN-114249640-A | Continuous production of methylpentene ketones using cation exchange resins in a fixed bed reactor | 印度孟买技术研究院 | 2022-03-29 | — | — | CN | disclosed |
| EP-3558980-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C N C C S S C A R L COLLEZIONE NAZ DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2021-01-27 | — | — | EP | disclosed |
| US-10815222-B2 | Compounds for use in the treatment of kinetoplastid infection | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2020-10-27 | — | — | US | disclosed |
| CN-111646880-A | Separation method for preparing glycol product from synthesis gas | 上海浦景化工技术股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-5480760-A | SULFONAMIDE THERMAL SOLVENT FOR IMPROVED DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5480761-A | CHROMOGENIC PHOTOGRAPHIC ELEMENTS WITH DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-4561451-A | 1,4-Diacylpiperazine flavored smoking compositions | PHILIP MORRIS INCORPORATED (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0116640-A4 | 1,4-DIACYLPIPERAZINE FLAVORED SMOKING COMPOSITIONS. | PHILIP MORRIS INC (US) | 1984-12-11 | — | — | EP | disclosed |
| EP-0116640-A1 | 1,4-DIACYLPIPERAZINE FLAVORED SMOKING COMPOSITIONS | PHILIP MORRIS INCORPORATED (US) | 1984-08-29 | — | — | EP | disclosed |
| WO-1984000672-A1 | 1,4-DIACYLPIPERAZINE FLAVORED SMOKING COMPOSITIONS | PHILIP MORRIS INC (US) | 1984-03-01 | — | — | WO | disclosed |