⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339877 | 0.91 | PTPN7 (0.41) | — | |
| SCHEMBL8045294 | 0.91 | PTPN7 (0.41) | — | |
| SCHEMBL6257072 | 0.91 | PTPN7 (0.41) | — | |
| SCHEMBL8949595 | 0.84 | — | — | |
| SCHEMBL19547103 | 0.83 | MAPT (0.46) | — | |
| SCHEMBL8614496 | 0.78 | — | — | |
| SCHEMBL15691473 | 0.78 | — | — | |
| SCHEMBL1771453 | 0.78 | TDP1 (0.60) | — | |
| SCHEMBL12673292 | 0.78 | TDP1 (0.60) | — | |
| SCHEMBL285143 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951548-B2 | Acrylic hydrogels with pendant cyclodextrins, preparation method thereof and use of same as release systems and contact lens components | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2015-02-10 | — | — | US | claimed |
| EP-1240157-A2 | SUBSTITUTED N-BENZYL-INDOL-3-YL GLYOXYLIC ACID DERIVATIVES HAVING AN ANTI-TUMORAL EFFECT | Zentaris AG (DE) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047913-A2 | SUBSTITUTED N-BENZYL-INDOL-3-YL GLYOXYLIC ACID DERIVATIVES HAVING AN ANTI-TUMORAL EFFECT | ZENTARIS AG (DE) | 2001-07-05 | — | — | WO | claimed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | claimed |
| CN-109280223-B | Resin composition and molded article | 富士胶片商业创新有限公司 | 2022-03-08 | — | — | CN | disclosed |
| US-20200297700-A1 | BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF | TOBIRA THERAPEUTICS INC (US) | 2020-09-24 | — | — | US | disclosed |
| US-10744132-B2 | Sustained-release buprenorphine formulations | Alar Pharmaceuticals, Inc. (TW) | 2020-08-18 | — | — | US | disclosed |
| EP-3512518-A1 | SUSTAINED-RELEASE BUPRENORPHINE FORMULATIONS BACKGROUND OF INVENTION | Alar Pharmaceuticals Inc. (TW) | 2019-07-24 | — | — | EP | disclosed |
| US-20190142823-A1 | SUSTAINED-RELEASE BUPRENORPHINE FORMULATIONS | Alar Pharmaceuticals, Inc. (TW) | 2019-05-16 | — | — | US | disclosed |
| US-20190038604-A1 | BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF | TOBIRA THERAPEUTICS, INC. (US) | 2019-02-07 | — | — | US | disclosed |
| WO-2018050043-A1 | SUSTAINED-RELEASE BUPRENORPHINE FORMULATIONS BACKGROUND OF INVENTION | ALAR PHARMACEUTICALS INC. (CN) | 2018-03-22 | — | — | WO | disclosed |
| EP-2258676-B1 | STABLE VINAMIDINIUM SALT AND NITROGEN-CONTAINING HETEROCYCLIC RING SYNTHESIS USING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-4459221-A | Fluorine-containing surface active composition | DAIKIN KOGYO CO., LTD. (JP) | 1984-07-10 | — | — | US | disclosed |
| EP-0043108-A1 | Fluorine-containing surface active composition | Daikin Kogyo Co., Ltd. (JP) | 1982-01-06 | — | — | EP | disclosed |
| US-4165323-A | ANALGESICS, TRANQUILIZERS | PFIZER INC. (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4111946-A | Preparation of 3-(pyridinyl)-2-cyclohexen-1-ones | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4041161-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4025316-A | POLYMERIC ALKYL HYDROXY BENZYL AMINES, DETERGENTS, ANTIOXIDANTS, GASOLINE, LUBRICATING OIL | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-4007190-A | ANTITUMOR, MICROBIOCIDE | MERCK & CO., INC. (US) | 1977-02-08 | — | — | US | disclosed |