Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444630 | 0.90 | KMT2A (0.50) | KMT2AALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL8949380 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL8444627 | 0.75 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2FLT1KDR | |
| SCHEMBL8949347 | 0.75 | CA12 (0.49) | KMT2AALDH1A1SMN1; SMN2KDM4EHTT | |
| Hydrochloric Acid SCHEMBL8949222 | 0.74 | CA12 (0.48) | KMT2AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL4410767 | 0.74 | KMT2A (0.63) | KMT2AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL8447413 | 0.71 | POLB (0.43) | KMT2AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL8445933 | 0.70 | HPGD (0.49) | KMT2AALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL992745 | 0.70 | SMN1; SMN2 (0.61) | KMT2AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL4298077 | 0.70 | KMT2A (0.57) | KMT2AALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |