Methacrylic Acid

Methacrylic Acid

SCHEMBL8949820

C=C(C)C(=O)O.C=C(C)C(=O)OCCO.C=C(C=C(C)C(=O)O)C(=O)OCCCC

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.51
THRB P10828 1/20 0.39
POLB P06746 2/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.35
HCAR2 Q8TDS4 3/20 0.35
ACHE P22303 1/20 0.34
MGLL Q99685 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7613106 0.93 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL725335 0.92 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9436100 0.89 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7730836 0.89 TSHR (0.67) TSHRTHRBPOLBAPEX1HTT
SCHEMBL168598 0.89 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9683138 0.88 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10798375 0.88 ALDH1A1 (0.53) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL7253551 0.87 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
Styrene SCHEMBL5947075 0.87 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
SCHEMBL459709 0.86 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532105-A HAVING GOOD ADHESION TO PLATED COPPER HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-07-02 US disclosed