Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459709 | 0.99 | TSHR (0.50) | TSHRALDH1A1THRBPOLBTDP1 | |
| Acrylic Acid SCHEMBL11794147 | 0.94 | TSHR (0.46) | TSHRALDH1A1THRBPOLBTDP1 | |
| SCHEMBL7974868 | 0.93 | TSHR (0.59) | TSHRALDH1A1THRBPOLBTDP1 | |
| SCHEMBL7730836 | 0.90 | TSHR (0.67) | TSHRALDH1A1THRBPOLBTDP1 | |
| SCHEMBL9436100 | 0.90 | TSHR (0.54) | TSHRALDH1A1THRBPOLBTDP1 | |
| Methacrylic Acid SCHEMBL725335 | 0.90 | TSHR (0.51) | TSHRALDH1A1THRBPOLBTDP1 | |
| SCHEMBL168598 | 0.90 | TSHR (0.50) | TSHRALDH1A1THRBPOLBTDP1 | |
| Methacrylic Acid SCHEMBL8949820 | 0.88 | TSHR (0.51) | TSHRALDH1A1THRBPOLBTDP1 | |
| SCHEMBL7871827 | 0.88 | TSHR (0.43) | TSHRALDH1A1THRBPOLBTDP1 | |
| SCHEMBL10531571 | 0.88 | ALDH1A1 (0.42) | TSHRALDH1A1THRBPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143788-A | Molded composite for automobile exteriors doesn't need painting | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| US-5122552-A | A curable mixture of an epoxy compound and a polyesterurethane having a carboxy-containing diol as a monomer; automobile finishes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-16 | — | — | US | disclosed |
| US-5000809-A | Laminate thermoformed to form a composite a polyesterurethane and a multifunctional crosslinking agent of an epoxy and an or ganic polyisocyanate | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |