Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.54 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.54 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950061 | 0.98 | GABBR2 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Butylamine SCHEMBL8949981 | 0.91 | GABBR2 (0.58) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Methyl Phosphonate SCHEMBL8008672 | 0.91 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21272021 | 0.91 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Octadecylamine SCHEMBL28212235 | 0.91 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL23525472 | 0.88 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL3406817 | 0.88 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hexadecylamine SCHEMBL8378529 | 0.88 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL9011419 | 0.88 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL7118141 | 0.88 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574024-A | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | EBETINO FRANK H (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |