Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.38 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.38 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.38 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273566 | 0.86 | GCGR (0.50) | GCGRCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL9267251 | 0.78 | GCGR (0.53) | GCGRCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL9271191 | 0.77 | GCGR (0.60) | GCGRSLC10A2MAPTKDM4EALDH1A1 | |
| SCHEMBL2648212 | 0.77 | GCGR (0.62) | GCGRSLC10A2MAPTMEN1KMT2A | |
| SCHEMBL27295913 | 0.75 | DHODH (0.46) | GCGR | |
| SCHEMBL2647009 | 0.74 | GAA (0.42) | GCGRCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL6957283 | 0.73 | ALDH1A1 (0.50) | GCGRCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL8949863 | 0.72 | CACNA1F (0.39) | CACNA1FACHECACNA1DCACNA1SCACNA1C | |
| SCHEMBL9269790 | 0.72 | GCGR (0.46) | GCGRCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL9269784 | 0.71 | GCGR (0.41) | GCGRCACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502057-A | Polysubstituted pyridines useful for treating lipoproteinanaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5470982-A | Disubstituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |
| US-5173495-A | 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-4968689-A | Certain 2,6-diisopropyl-4-(4-fluoro-phenyl)-3,5-bis-dimethyl-3',5'-dihydroxy-hept-6-enoate-pyridine derivatives useful for treating lipoproteinaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |