Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647302 | 0.90 | GCGR (0.48) | GCGRSLC10A2TRPM8ALDH1A1L3MBTL1 | |
| SCHEMBL9152685 | 0.85 | GCGR (0.45) | GCGRSLC10A2TRPM8ALDH1A1L3MBTL1 | |
| SCHEMBL9743385 | 0.83 | TRPM8 (0.38) | GCGRSLC10A2TRPM8ALDH1A1L3MBTL1 | |
| SCHEMBL9273566 | 0.82 | GCGR (0.50) | GCGRSLC10A2TRPM8ALDH1A1L3MBTL1 | |
| SCHEMBL6963404 | 0.82 | GCGR (0.47) | GCGRPRKAA2 | |
| SCHEMBL9271191 | 0.81 | GCGR (0.60) | GCGRSLC10A2TRPM8ALDH1A1L3MBTL1 | |
| SCHEMBL6953311 | 0.80 | GCGR (0.49) | GCGRPRKAA2 | |
| SCHEMBL9267251 | 0.78 | GCGR (0.53) | GCGRSLC10A2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9269790 | 0.77 | GCGR (0.46) | GCGRSLC10A2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2648212 | 0.75 | GCGR (0.62) | GCGRSLC10A2TRPM8ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401746-A | FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND HMG-COA REDUCTASE | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5169857-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |
| US-5006530-A | Certain 7-[2,6-diisopropyl-4-phenyl-5-lower alkoxymethyl-pyrid-3-yl]-3,5-dihydroxy-6-enoates and derivatives useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |