⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18951907 | 0.91 | PIK3CD (0.35) | — | |
| SCHEMBL22448448 | 0.84 | — | — | |
| SCHEMBL18951857 | 0.84 | CES2 (0.36) | — | |
| SCHEMBL10076693 | 0.84 | — | — | |
| Tetrahydrofuran SCHEMBL27796884 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL5084320 | 0.84 | — | — | |
| SCHEMBL417400 | 0.82 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL13751193 | 0.79 | PIK3CD (0.37) | — | |
| SCHEMBL76462 | 0.78 | — | — | |
| SCHEMBL2617044 | 0.78 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 711 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026995-A | Dihydrotriazole aromatization precursor and application thereof in deacylating and arylating reaction of ketone | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | claimed |
| EP-2697227-A1 | FUSED IMIDAZOLE DERIVATIVES USEFUL AS IDO INHIBITORS | Newlink Genetics Corporation (US) | 2014-02-19 | — | — | EP | claimed |
| WO-2012142237-A1 | FUSED IMIDAZOLE DERIVATIVES USEFUL AS IDO INHIBITORS | NEWLINK GENETICKS CORPORATION (US) | 2012-10-18 | — | — | WO | claimed |
| US-7741497-B2 | Processes for preparing alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound and 4-acyltetrahydropyrane | UBE INDUSTRIES, LTD. (JP) | 2010-06-22 | — | — | US | claimed |
| US-12637468-B2 | Substituted [1,2,4]triazolo[4,3-b]pyridazines as GABAA receptor modulators | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2026-05-26 | — | — | US | disclosed |
| CN-122036613-A | Phenyl-pyrazole-phencyclipropylamine derivative and application thereof | 郑州大学 | 2026-05-15 | — | — | CN | disclosed |
| US-12583858-B2 | TDO2 inhibitors | GENENTECH, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| US-20260027106-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2026-01-29 | — | — | US | disclosed |
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |
| US-20250288589-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | Kineta, Inc. | 2025-09-18 | — | — | US | disclosed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |
| WO-2003099276-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| US-20030138791-A1 | 3-Spiro-cyanin fluorochromes and their use in bioassays | HAALCK LUTZ (DE) | 2003-07-24 | — | — | US | disclosed |
| EP-1320571-A1 | 3-SPIRO-CYANIN FLUOROCHROMES AND THEIR USE IN BIOASSAYS | INSTITUT FÜR CHEMO- UND BIOSENSORIK Münster e.V. (DE) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002026890-A1 | 3-SPIRO-CYANIN FLUOROCHROMES AND THEIR USE IN BIOASSAYS | Institut für Chemo- und Biosensorik Münster E.V. (DE) | 2002-04-04 | — | — | WO | disclosed |
| JP-2001172274-A | METHOD FOR PRODUCING 4-ACETYLTETRAHYDROPYRANE | UBE IND LTD | 2001-06-26 | — | — | JP | disclosed |
| US-5370956-A | With layer containing inorganic photoconductor, binder and sensitizing dye, high sensitivity to red light, storage stability, for scanning exposure with semiconductor laser beam | MITSUBISHI PAPER MILLS LIMITED (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5077186-A | Indole dyes with at least three acid groups; antihalants | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-12-31 | — | — | US | disclosed |