SCHEMBL8950260

SCHEMBL8950260

O=C1CC(=O)N2CCCN12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
BRD2 P25440 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2514082 0.93 BRD4 (0.33) BRD4BRD2LMNA
SCHEMBL31379283 0.81
SCHEMBL14559892 0.80 BRD4 (0.39) BRD4BRD2LMNA
SCHEMBL600282 0.73 BRD4 (0.52) BRD4BRD2LMNA
SCHEMBL12450880 0.73 CHRM2 (0.39) BRD4BRD2LMNA
SCHEMBL5530657 0.72
SCHEMBL1440028 0.71 BRD4 (0.43) BRD4BRD2LMNA
SCHEMBL12443428 0.71 BRD4 (0.43) BRD4BRD2LMNA
SCHEMBL11382367 0.69 BRD4 (0.42) BRD4BRD2LMNA
SCHEMBL4475232 0.69 CYP2A6 (0.33) BRD4BRD2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0577629-B1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA GEIGY AG (CH) 1996-06-26 EP claimed
US-5494890-A FOR CONTROLLING WEEDS, INSECTS, MITES CIBA-GEIGY CORPORATION (US) 1996-02-27 US claimed
EP-0577629-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS. CIBA GEIGY AG (CH) 1994-01-12 EP claimed
WO-1992016510-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA-GEIGY AG (CH) 1992-10-01 WO claimed
EP-0577629-B1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA GEIGY AG (CH) 1996-06-26 EP disclosed
US-5506193-A Herbicidally, acaricidally and insecticidally active pyrazolidine compounds CIBA-GEIGY CORPORATION (US) 1996-04-09 US disclosed
US-5494890-A FOR CONTROLLING WEEDS, INSECTS, MITES CIBA-GEIGY CORPORATION (US) 1996-02-27 US disclosed
EP-0577629-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS. CIBA GEIGY AG (CH) 1994-01-12 EP disclosed
WO-1992016510-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA-GEIGY AG (CH) 1992-10-01 WO disclosed