Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950363 | 0.79 | CA2 (0.53) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950393 | 0.74 | KMT2A (0.36) | CA2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7938911 | 0.73 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950392 | 0.73 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| Hydrochloric Acid SCHEMBL7764015 | 0.73 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| Hydrochloric Acid SCHEMBL5617307 | 0.72 | CYP2D6 (0.43) | — | |
| SCHEMBL9057591 | 0.71 | APOBEC3G (0.30) | — | |
| SCHEMBL6473544 | 0.70 | DRD2 (0.48) | LMNA | |
| Hydrochloric Acid SCHEMBL5655044 | 0.70 | DRD2 (0.48) | LMNA | |
| SCHEMBL8950595 | 0.69 | CA2 (0.33) | CA2CA4CA12CA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |