Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.57 |
| ▸ | CA4 | P22748 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950415 | 0.95 | CA2 (0.58) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950096 | 0.94 | CA2 (0.57) | CA2CA4 | |
| SCHEMBL8950382 | 0.89 | CA2 (0.62) | CA2CA4CA12CA1CA6 | |
| Hydrochloric Acid SCHEMBL8950454 | 0.89 | CA2 (0.61) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950346 | 0.86 | CA2 (0.55) | CA2CA4PTGS2CA1CA9 | |
| Hydrochloric Acid SCHEMBL8950267 | 0.86 | CA2 (0.55) | CA2CA4PTGS2 | |
| SCHEMBL8950210 | 0.86 | CA2 (0.64) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950455 | 0.86 | CA2 (0.61) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950207 | 0.85 | CA2 (0.54) | CA2CA4 | |
| SCHEMBL8950256 | 0.84 | CA2 (0.64) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |