Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8950267 | 0.99 | CA2 (0.55) | CA2CA4L3MBTL1ABL1RIN1 | |
| SCHEMBL8950314 | 0.86 | CA2 (0.57) | CA2CA4PTGS2CA1CA9 | |
| SCHEMBL8950408 | 0.85 | CA2 (0.62) | CA2CA4CA1CA9 | |
| SCHEMBL8950415 | 0.84 | CA2 (0.58) | CA2CA4L3MBTL1 | |
| SCHEMBL8950382 | 0.84 | CA2 (0.62) | CA2CA4CA1CA9 | |
| SCHEMBL8950455 | 0.84 | CA2 (0.61) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950254 | 0.84 | CA2 (0.61) | CA2CA4 | |
| SCHEMBL8950259 | 0.84 | CA2 (0.63) | CA2CA4CA1CA9 | |
| Hydrochloric Acid SCHEMBL8950096 | 0.84 | CA2 (0.57) | CA2CA4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8950454 | 0.84 | CA2 (0.61) | CA2CA4CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | claimed |
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |