Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21954365 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HTTPTPN1KMT2AMEN1 | |
| SCHEMBL789581 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HTTPTPN1KMT2AMEN1 | |
| SCHEMBL84296 | 0.75 | PTPN1 (0.50) | ALDH1A1HTTPTPN1KMT2AMEN1 | |
| SCHEMBL31405756 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HTTPTPN1KMT2AMEN1 | |
| SCHEMBL28006934 | 0.74 | PTPN1 (0.53) | ALDH1A1HTTPTPN1KMT2AMEN1 | |
| SCHEMBL30695267 | 0.74 | PTPN1 (0.53) | ALDH1A1HTTPTPN1KMT2AMEN1 | |
| SCHEMBL23788789 | 0.72 | MAOB (0.43) | PTPN1MAOAMAOBGAA | |
| SCHEMBL8950005 | 0.71 | HTR1A (0.60) | ALDH1A1HTTPTPN1 | |
| SCHEMBL6835355 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HTTPTPN1KMT2AMEN1 | |
| SCHEMBL13726243 | 0.71 | PTPN1 (0.50) | ALDH1A1HTTPTPN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494910-A | TREATING MIGRAINE AND OTHER TYPES OF HEADACHE | GLAXO GROUP LIMITED (GB) | 1996-02-27 | — | — | US | disclosed |