SCHEMBL8950411

SCHEMBL8950411

CC(C)=COc1ccccc1C=NO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.54
ALDH1A1 P00352 3/20 0.54
LMNA P02545 6/20 0.53
HTT P42858 3/20 0.53
MAPT P10636 4/20 0.51
MAPK1 P28482 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 1/20 0.50
USP2 O75604 2/20 0.47
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4370639 0.78 CA1 (0.39) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL9157736 0.78 ALDH1A1 (0.39) HPGDALDH1A1LMNAHTTMAPK1
SCHEMBL5049336 0.78 HPGD (0.62) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL2160888 0.77 HPGD (0.69) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL30210927 0.77 HPGD (0.69) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL2160891 0.77 HPGD (0.69) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL2420718 0.77 HPGD (0.69) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL8943589 0.75 HPGD (0.50) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL11672212 0.73 HPGD (0.71) HPGDALDH1A1LMNAHTTMAPT
SCHEMBL7602964 0.73 HPGD (0.61) HPGDALDH1A1LMNAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518510-A EXHAUST SYSTEMS WITH TRAPS FOR DIESEL ENGINES THE LUBRIZOL CORPORATION (US) 1996-05-21 US claimed
US-5376154-A For diesel engines equipped with an exhaust system particulate trap; lowers ignition temperature of those particles THE LUBRIZOL CORPORATION (US) 1994-12-27 US claimed
US-5340369-A To lower ignition temperature of particles collected in exhaust system trap THE LUBRIZOL CORPORATION (US) 1994-08-23 US claimed
EP-0539572-A1 LOW-SULFUR DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES The Lubrizol Corporation (US) 1993-05-05 EP claimed
EP-0238629-B1 COMPOSITION COMPRISING A TRANSITION METAL OR LEAD COMPLEX OF A MANNICH BASE AND AN OXIM AND ITS USE AS A FUEL ADDITIVE The Lubrizol Corporation (US) 1992-12-02 EP claimed
CN-1066676-A Diesel fuel containing organometallic complexes LUBRIZOL CORP (US) 1992-12-02 CN claimed
CN-1066675-A The low-sulfur diesel fuels that contains organometallic complex LUBRIZOL CORP (US) 1992-12-02 CN claimed
WO-1992020762-A1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1992-11-26 WO claimed
WO-1992020763-A1 LOW-SULFUR DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO claimed
WO-1992020765-A1 DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO claimed
EP-0238629-A1 COMPOSITION COMPRISING A TRANSITION METAL OR LEAD COMPLEX OF A MANNICH BASE AND AN OXIM AND ITS USE AS A FUEL ADDITIVE. LUBRIZOL CORP (US) 1987-09-30 EP claimed
US-4673412-A STORAGE STABILITY THE LUBRIZOL CORPORATION (US) 1987-06-16 US claimed
CN-86106275-A The fuel dope and the fuel composition thereof that contain metallic compound and oxime 1987-05-13 CN claimed
WO-1987001720-A1 FUEL ADDITIVE COMPRISING A METAL COMPOUND AND AN OXIME AND FUEL COMPOSITIONS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1987-03-26 WO claimed
EP-0539576-B1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME LUBRIZOL CORP (US) 1996-05-29 EP disclosed
US-5518510-A EXHAUST SYSTEMS WITH TRAPS FOR DIESEL ENGINES THE LUBRIZOL CORPORATION (US) 1996-05-21 US disclosed
US-5376154-A For diesel engines equipped with an exhaust system particulate trap; lowers ignition temperature of those particles THE LUBRIZOL CORPORATION (US) 1994-12-27 US disclosed
WO-1992020763-A1 LOW-SULFUR DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
WO-1992020765-A1 DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
US-4673412-A STORAGE STABILITY THE LUBRIZOL CORPORATION (US) 1987-06-16 US disclosed