Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 16/20 | 0.41 |
| ▸ | GABRD | O14764 | 16/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 16/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 16/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 16/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 16/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 16/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 16/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 16/20 | 0.41 |
| ▸ | GABRE | P78334 | 16/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 16/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 16/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 16/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 16/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950467 | 0.79 | KDM1A (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950474 | 0.79 | KDM1A (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950620 | 0.79 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950535 | 0.78 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950700 | 0.76 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950513 | 0.72 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23126972 | 0.70 | OPRL1 (0.40) | KDM1A | |
| SCHEMBL8950501 | 0.67 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950505 | 0.67 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11366020 | 0.66 | NUDT1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502073-A | INSECTICIDES OR ANTHELMINTICS | THE WELLCOME FOUNDATION (GB) | 1996-03-26 | — | — | US | disclosed |