⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675755 | 0.75 | — | — | |
| SCHEMBL730082 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL27675954 | 0.73 | — | — | |
| SCHEMBL17237464 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL6244314 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL17460318 | 0.69 | FFAR3 (0.38) | — | |
| SCHEMBL646068 | 0.67 | TSHR (0.36) | — | |
| SCHEMBL4275231 | 0.67 | TSHR (0.36) | — | |
| SCHEMBL18100552 | 0.67 | FFAR3 (0.36) | — | |
| SCHEMBL29110927 | 0.67 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651770-A1 | ANTIHEMOPHILIC FACTOR STABILIZATION | JOHNSON, Alan J. (US) | 1995-05-10 | — | — | EP | claimed |
| EP-0651770-A4 | ANTIHEMOPHILIC FACTOR STABILIZATION. | JOHNSON ALAN J (US) | 1995-03-23 | — | — | EP | claimed |
| WO-1993010143-A1 | ANTIHEMOPHILIC FACTOR STABILIZATION | JOHNSON ALAN J (US) | 1993-05-27 | — | — | WO | claimed |
| US-5484890-A | FACTOR VIII WITH STABILIZERS | JOHNSON ALAN J (US) | 1996-01-16 | — | — | US | disclosed |
| EP-0651770-A1 | ANTIHEMOPHILIC FACTOR STABILIZATION | JOHNSON, Alan J. (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0651770-A4 | ANTIHEMOPHILIC FACTOR STABILIZATION. | JOHNSON ALAN J (US) | 1995-03-23 | — | — | EP | disclosed |
| US-5278289-A | Purification by ionic exchanging | JOHNSON ALAN J (US) | 1994-01-11 | — | — | US | disclosed |
| WO-1993010143-A1 | ANTIHEMOPHILIC FACTOR STABILIZATION | JOHNSON ALAN J (US) | 1993-05-27 | — | — | WO | disclosed |