Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952075 | 0.88 | PLA2G2D (0.37) | CHRM4IDO1FFAR4RORCCXCR2 | |
| SCHEMBL1256244 | 0.81 | ALOX15 (0.40) | CHRM4IDO1FFAR4CXCR2NR1H2 | |
| SCHEMBL29710998 | 0.79 | ALOX5 (0.41) | FFAR4ATRCTNNB1WNT3ACYP2C9 | |
| SCHEMBL9726223 | 0.79 | FFAR4 (0.36) | CHRM4IDO1FFAR4CXCR2NR1H2 | |
| SCHEMBL1902302 | 0.78 | IDO1 (0.40) | IDO1FFAR4CXCR2ATRCTNNB1 | |
| SCHEMBL4764043 | 0.78 | PARP1 (0.44) | FFAR4ATRMAPT | |
| Hydrochloric Acid SCHEMBL9235440 | 0.78 | ALOX5 (0.41) | CHRM4FFAR4ATRCTNNB1WNT3A | |
| SCHEMBL10687705 | 0.78 | FFAR4 (0.36) | CHRM4IDO1FFAR4CXCR2NR1H2 | |
| SCHEMBL637798 | 0.75 | PTPN1 (0.44) | CHRM4IDO1FFAR4ATRCTNNB1 | |
| SCHEMBL8886611 | 0.74 | PDK2 (0.39) | IDO1FFAR4ATRCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514816-A | REACTION OF DIFLUOROBENZO-1,3-DIOXOLE WITH METAL COMPOUNDS FOR INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-05-07 | — | — | US | disclosed |
| US-5496848-A | Process for the preparation of substituted difluorobenzo-1,3-dioxoles | CIBA-GEIGY CORPORATION (US) | 1996-03-05 | — | — | US | disclosed |
| US-5493032-A | INSECTICIDES, MICROBIOCIDES | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0333658-B1 | Process for the preparation of substituted difluorbenzo-1,3-dioxoles | CIBA GEIGY AG (CH) | 1995-07-26 | — | — | EP | disclosed |
| US-5420301-A | Process for the preparation of substituted difluorobenzo-1,3-dioxoles | CIBA-GEIGY CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| US-5281718-A | Reacting in one pot reaction 2,2-difluorobenzodioxole with an organometal compound or metal to form 4-metallo-2,2-difluorobenzodioxole, reacting with unsaturated nitrile, then with isocyanide | CIBA-GEIGY CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| US-5194628-A | Reacting metallo-difluorobenzodioxole with unsaturated nitrile and then with sulfonylmethyl isocyanide | CIBA-GEIGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0333658-A2 | Process for the preparation of substituted difluorbenzo-1,3-dioxoles | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | disclosed |