Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952173 | 1.00 | PLAU (0.47) | PLAUSIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL6724185 | 0.85 | SIGMAR1 (0.54) | PLAUSIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL7443927 | 0.79 | SIGMAR1 (0.49) | SIGMAR1MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL7443919 | 0.79 | SIGMAR1 (0.49) | SIGMAR1MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL7492189 | 0.78 | SIGMAR1 (0.46) | SIGMAR1MEN1KMT2AFAAHCNR2 | |
| SCHEMBL8952127 | 0.75 | SIGMAR1 (0.44) | SIGMAR1MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL8952146 | 0.74 | SIGMAR1 (0.51) | SIGMAR1MEN1KMT2AFAAHCNR2 | |
| SCHEMBL8952147 | 0.74 | SIGMAR1 (0.51) | SIGMAR1MEN1KMT2AFAAHCNR2 | |
| SCHEMBL6724175 | 0.71 | SIGMAR1 (0.58) | SIGMAR1L3MBTL1MEN1KMT2APAX8 | |
| SCHEMBL8866289 | 0.70 | SIGMAR1 (0.56) | SIGMAR1L3MBTL1MEN1KMT2APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552443-A | TREATMENT OF PSYCHOSIS, ANXIETY AND AS HYPOTENSIVE AGENTS | OREGON HEALTH SCIENCES UNIVERSITY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5308869-A | TREATMENT OR PROPHYLAXIS OF ANXIETY IN AN ANIMAL | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION (US) | 1994-05-03 | — | — | US | disclosed |