Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952146 | 1.00 | SIGMAR1 (0.51) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL6724211 | 0.81 | SIGMAR1 (0.58) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL7443919 | 0.80 | SIGMAR1 (0.49) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL7443927 | 0.80 | SIGMAR1 (0.49) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL7492189 | 0.79 | SIGMAR1 (0.46) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL8952127 | 0.77 | SIGMAR1 (0.44) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL8952173 | 0.74 | PLAU (0.47) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL8952174 | 0.74 | PLAU (0.47) | SIGMAR1FAAHMEN1KMT2AEPHX2 | |
| SCHEMBL8952148 | 0.71 | EPHX2 (0.49) | FAAHKMT2AEPHX2CNR2CNR1 | |
| SCHEMBL9440893 | 0.70 | SIGMAR1 (0.50) | SIGMAR1FAAHMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552443-A | TREATMENT OF PSYCHOSIS, ANXIETY AND AS HYPOTENSIVE AGENTS | OREGON HEALTH SCIENCES UNIVERSITY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5308869-A | TREATMENT OR PROPHYLAXIS OF ANXIETY IN AN ANIMAL | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION (US) | 1994-05-03 | — | — | US | disclosed |