Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952184 | 0.90 | SIGMAR1 (0.44) | SIGMAR1CNR2FAAHNPC1RAB9A | |
| SCHEMBL6719600 | 0.86 | SIGMAR1 (0.54) | SIGMAR1CNR2FAAHNPC1RAB9A | |
| SCHEMBL7443927 | 0.81 | SIGMAR1 (0.49) | SIGMAR1CNR2FAAHMAPTALDH1A1 | |
| SCHEMBL7443919 | 0.81 | SIGMAR1 (0.49) | SIGMAR1CNR2FAAHMAPTALDH1A1 | |
| SCHEMBL9316280 | 0.77 | EPHX2 (0.40) | SIGMAR1CNR2FAAHNPC1RAB9A | |
| SCHEMBL9317615 | 0.77 | SIGMAR1 (0.45) | SIGMAR1CNR2NPC1RAB9AMAPT | |
| SCHEMBL7492189 | 0.71 | SIGMAR1 (0.46) | SIGMAR1CNR2FAAHMAPTALDH1A1 | |
| SCHEMBL6719597 | 0.71 | CNR2 (0.45) | SIGMAR1CNR2NPC1RAB9AMAPT | |
| SCHEMBL8952043 | 0.70 | SIGMAR1 (0.56) | SIGMAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8952040 | 0.70 | SIGMAR1 (0.56) | SIGMAR1NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552443-A | TREATMENT OF PSYCHOSIS, ANXIETY AND AS HYPOTENSIVE AGENTS | OREGON HEALTH SCIENCES UNIVERSITY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5308869-A | TREATMENT OR PROPHYLAXIS OF ANXIETY IN AN ANIMAL | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION (US) | 1994-05-03 | — | — | US | disclosed |