Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 9/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466778 | 0.95 | AHR (0.73) | AHRPTPN1MCL1CD44ALDH1A1 | |
| SCHEMBL13672099 | 0.91 | AHR (0.73) | AHRPTPN1MCL1ALDH1A1TSHR | |
| SCHEMBL29403123 | 0.85 | AHR (1.00) | AHRNPSR1 | |
| SCHEMBL548471 | 0.85 | AHR (1.00) | AHRNPSR1 | |
| SCHEMBL14033698 | 0.83 | PTPN1 (0.56) | AHRPTPN1MCL1ALDH1A1RAB9A | |
| SCHEMBL6466427 | 0.77 | AHR (0.76) | AHR | |
| SCHEMBL9927891 | 0.75 | AHR (0.46) | AHRMCL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL6466410 | 0.74 | AHR (0.70) | AHRMCL1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6468968 | 0.72 | AHR (0.60) | AHRMCL1 | |
| SCHEMBL22019093 | 0.72 | AHR (0.49) | AHRALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516790-A | Synthesis and application of alkyl-substituted dibenzofurans as antitumorigenic agents | TEXAS A&M UNIVERSITY SYSTEM TECHNOLOGY LICENSING OFFICE (US) | 1996-05-14 | — | — | US | disclosed |