Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952206 | 0.85 | EPHX2 (0.32) | MAPK1ALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL6944697 | 0.85 | MAPT (0.37) | MAPK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8803670 | 0.84 | TK1 (0.43) | MAPK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8803812 | 0.82 | HSD17B10 (0.34) | MAPK1ALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL9229524 | 0.82 | MAPK10 (0.33) | MAPK1HPGDEPHX2 | |
| SCHEMBL9027308 | 0.81 | HSD17B10 (0.34) | MAPK1ALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL9118291 | 0.81 | HSD17B10 (0.34) | MAPK1ALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL8802655 | 0.81 | HSD17B10 (0.34) | MAPK1ALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL7201249 | 0.81 | HSD17B10 (0.34) | MAPK1ALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL8952197 | 0.81 | HSD17B10 (0.34) | MAPK1ALDH1A1HPGDHSD17B10EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697873-A4 | — | — | 1996-04-03 | — | — | EP | claimed |
| EP-0697873-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-02-28 | — | — | EP | claimed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | claimed |
| EP-0662834-A4 | NOVEL EPOXIDE-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0697873-A4 | — | — | 1996-04-03 | — | — | EP | disclosed |
| EP-0697873-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0662834-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| WO-1994006431-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-03-31 | — | — | WO | disclosed |