Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.60 |
| ▸ | ADH1B | P00325 | 3/20 | 0.55 |
| ▸ | ADH1C | P00326 | 3/20 | 0.55 |
| ▸ | ADH1A | P07327 | 3/20 | 0.55 |
| ▸ | ADH7 | P40394 | 3/20 | 0.55 |
| ▸ | ADH4 | P08319 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861073 | 1.00 | SIGMAR1 (0.60) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL303075 | 0.98 | ADH1B (0.57) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL22104300 | 0.96 | ADH1B (0.54) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL304406 | 0.94 | ADH1B (0.57) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL3024930 | 0.92 | ADH1B (0.54) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL5646910 | 0.85 | ADH1B (0.61) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL302803 | 0.85 | ADH1B (0.61) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL5651899 | 0.83 | — | — | |
| SCHEMBL5649841 | 0.83 | ADH1B (0.58) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL10684366 | 0.79 | SIGMAR1 (0.54) | SIGMAR1ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506239-A | Carbostyril derivative and platelets aggregation inhibitory agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0569592-A1 | CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-18 | — | — | EP | disclosed |