Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085666 | 0.87 | MAPK10 (0.44) | MAPK10MEN1KMT2AALDH1A1XBP1 | |
| SCHEMBL8952508 | 0.86 | KDM4E (0.36) | EPHX2MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL8952586 | 0.86 | KDM4E (0.36) | EPHX2MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL8952620 | 0.86 | KDM4E (0.36) | EPHX2MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL8952638 | 0.86 | KDM4E (0.36) | EPHX2MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL8952591 | 0.86 | KDM4E (0.36) | EPHX2MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL6944697 | 0.84 | MAPT (0.37) | EPHX2MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL9229524 | 0.84 | MAPK10 (0.33) | EPHX2MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL9116975 | 0.83 | PAOX (0.36) | EPHX2MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL8952345 | 0.83 | HSD17B10 (0.34) | EPHX2MAPK10MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714302-A4 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS INC (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0714302-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1994022449-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |