Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 10/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952618 | 0.87 | TK1 (0.41) | TK1PNPHPRT1KDM4ELMNA | |
| SCHEMBL27483073 | 0.83 | KMT2A (0.48) | TK1KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL28151874 | 0.82 | TK1 (0.50) | TK1HPRT1KDM4ELMNAPOLB | |
| SCHEMBL9385871 | 0.80 | CYP2C19 (0.36) | TK1HPRT1LMNAMAPK1CYP2C9 | |
| SCHEMBL9120166 | 0.80 | RXFP1 (0.49) | TK1PNPHPRT1KDM4ELMNA | |
| SCHEMBL5093664 | 0.79 | PNP (0.41) | TK1PNPHPRT1KDM4ELMNA | |
| SCHEMBL8952234 | 0.79 | MAPK1 (0.40) | TK1PNPHPRT1KDM4ELMNA | |
| SCHEMBL9682194 | 0.79 | MAPK1 (0.60) | KDM4ELMNAPOLBMAPK1KMT2A | |
| SCHEMBL8952352 | 0.79 | MAPK1 (0.40) | TK1PNPHPRT1KDM4ELMNA | |
| SCHEMBL652922 | 0.78 | MAPK1 (0.39) | KDM4ELMNAPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669825-A4 | HYDROXYL-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0669825-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994011001-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-05-26 | — | — | WO | disclosed |