SCHEMBL895276

SCHEMBL895276

O=C(O)C1CCC(Cl)(C(=O)O)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 3/20 0.47
GRM3 Q14832 3/20 0.47
TSHR P16473 3/20 0.47
LMNA P02545 3/20 0.47
GRM4 Q14833 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP1A2 P05177 2/20 0.47
ALOX15 P16050 2/20 0.47
GRM8 O00222 2/20 0.47
GRM6 O15303 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
GRM5 P41594 1/20 0.47
MTOR P42345 1/20 0.47
GRM1 Q13255 1/20 0.47
PLCB1 Q9NQ66 1/20 0.47
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4372279 0.86 GRM4 (0.53) GRM2GRM3TSHRLMNAGRM4
SCHEMBL11820173 0.85 CYP2C19 (0.35) GRM2GRM3TSHRLMNAGRM4
SCHEMBL11239624 0.84 MAPT (0.40) GRM2GRM3TSHRLMNAGRM4
SCHEMBL29919375 0.80 TSHR (0.45) GRM2GRM3TSHRLMNAGRM4
SCHEMBL4264213 0.80 EPHX2 (0.32) GRM2GRM3TSHRLMNAGRM4
SCHEMBL11815538 0.76
SCHEMBL11818082 0.76 GRM4 (0.31) GRM4
SCHEMBL7000654 0.76 CYP2C19 (0.36) LMNACYP2C19CYP1A2MTORPMP22
SCHEMBL22324 0.76
SCHEMBL28961022 0.75 GRM2 (0.50) GRM2GRM3TSHRLMNAGRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118142347-A Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer 中国石油大学(华东) 2024-06-07 CN claimed
CN-115850117-B Method for preparing 1, 4-cyclohexane diisocyanate 黎明化工研究设计院有限责任公司 2024-06-04 CN claimed
CN-118085274-A Polyamide precoating resin, preparation method thereof and polyamide resin coating 浙江鹏孚隆科技股份有限公司 2024-05-28 CN claimed
CN-117946391-A Micro-crosslinking polyimide resin, polyimide film and preparation method thereof 华为技术有限公司 2024-04-30 CN claimed
CN-117946392-A Terminal group crosslinked polyimide resin, polyimide film and preparation method thereof 华为技术有限公司 2024-04-30 CN claimed
CN-117844392-A OCA (optical adhesive tape adhesive) with high-adhesion and low-adhesion multilayer structure for optical bonding and preparation method thereof 睿合科技有限公司 2024-04-09 CN claimed
WO-2023231317-A1 NANOFILTRATION MEMBRANE PREPARATION METHOD AND NANOFILTRATION MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2023-12-07 WO claimed
CN-116769161-A Polyimide with low CTE and high light transmittance, diamine monomer thereof and preparation method thereof 河北科技大学 2023-09-19 CN claimed
CN-112062949-B Semi-aromatic polyamino acid, semi-aromatic polyamino acid-based bone repair material and preparation thereof 中鼎凯瑞科技成都有限公司 2023-04-25 CN claimed
CN-112717721-B Acid-resistant composite nanofiltration membrane and preparation method thereof 湖南澳维科技股份有限公司 2023-03-31 CN claimed
CN-112870990-A Antibacterial and pollution-resistant reverse osmosis composite membrane and preparation method thereof 中化(宁波)润沃膜科技有限公司 2021-06-01 CN claimed
CN-107428672-B Mixture of polymerizable compounds and method for producing same 日本瑞翁株式会社 2021-05-14 CN claimed
CN-112717721-A Acid-resistant composite nanofiltration membrane and preparation method thereof 湖南澳维环保科技有限公司 2021-04-30 CN claimed
CN-112717717-A Polysulfone-based membrane, reverse osmosis composite membrane containing same and preparation method 中化(宁波)润沃膜科技有限公司 2021-04-30 CN claimed
CN-112062949-A Semi-aromatic polyamino acid, semi-aromatic polyamino acid-based bone repair material and preparation thereof 中鼎凯瑞科技成都有限公司 2020-12-11 CN claimed
CN-107151204-B Method for producing 1, 4-cyclohexanedicarboxylic acid chloride 东丽精细化工株式会社 2020-10-23 CN claimed
CN-108079806-B Polyamide semipermeable membrane, preparation method and application thereof 浙江大学 2020-09-08 CN claimed
CN-108291999-B Optical film, polarizing plate, image display device, polymerizable compound, and method for producing 1, 4-cyclohexanedicarboxylic acid monoaryl ester 富士胶片株式会社 2020-07-10 CN claimed
CN-111068526-A Desalination composite membrane and preparation method thereof 中化(宁波)润沃膜科技有限公司 2020-04-28 CN claimed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US claimed