Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952794 | 1.00 | SQOR (0.32) | SQORKDM4ELMNAALDH1A1ALOX12 | |
| SCHEMBL8953142 | 0.94 | SQOR (0.39) | SQOR | |
| SCHEMBL8953147 | 0.94 | SQOR (0.39) | SQOR | |
| SCHEMBL8953026 | 0.88 | HMGCR (0.31) | — | |
| SCHEMBL8953017 | 0.88 | HMGCR (0.31) | — | |
| SCHEMBL8952912 | 0.88 | FABP4 (0.32) | — | |
| SCHEMBL8952904 | 0.88 | FABP4 (0.32) | — | |
| SCHEMBL8953059 | 0.87 | SQOR (0.36) | SQORKDM4ELMNAALDH1A1ALOX12 | |
| SCHEMBL8953066 | 0.87 | SQOR (0.36) | SQORKDM4ELMNAALDH1A1ALOX12 | |
| SCHEMBL8952949 | 0.87 | GCGR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |