Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 5/20 | 0.48 |
| ▸ | FNTB | P49356 | 5/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953498 | 1.00 | HDAC2 (0.51) | HDAC2FNTAFNTBSLC6A5PGGT1B | |
| SCHEMBL18619952 | 0.87 | FNTA (0.52) | HDAC2FNTAFNTBSLC6A5PGGT1B | |
| SCHEMBL15297196 | 0.85 | SLC6A5 (0.64) | HDAC2FNTAFNTBSLC6A5PGGT1B | |
| SCHEMBL302152 | 0.85 | FNTA (0.58) | HDAC2FNTAFNTBPGGT1BNOD1 | |
| SCHEMBL302151 | 0.85 | FNTA (0.58) | HDAC2FNTAFNTBPGGT1BNOD1 | |
| SCHEMBL5069979 | 0.84 | SLC6A5 (0.70) | HDAC2FNTAFNTBSLC6A5PGGT1B | |
| SCHEMBL11418516 | 0.84 | SLC6A5 (0.70) | HDAC2FNTAFNTBSLC6A5PGGT1B | |
| SCHEMBL20398927 | 0.84 | SLC6A5 (0.70) | HDAC2FNTAFNTBSLC6A5PGGT1B | |
| SCHEMBL22424713 | 0.84 | SLC6A5 (0.70) | HDAC2FNTAFNTBSLC6A5PGGT1B | |
| SCHEMBL5662648 | 0.84 | SLC6A5 (0.70) | HDAC2FNTAFNTBSLC6A5PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666738-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE. | MERCK & CO INC (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0666738-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1995-08-16 | — | — | EP | disclosed |