Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.70 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | FAAH | O00519 | 5/20 | 0.55 |
| ▸ | FNTA | P49354 | 2/20 | 0.54 |
| ▸ | FNTB | P49356 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027056 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL5662643 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL15650190 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL5662648 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL5662639 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL11418516 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL20398927 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL11420979 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL22424713 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA | |
| SCHEMBL5662646 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1EPHX2FAAHFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914223-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL plc (GB) | 2008-04-23 | — | — | EP | claimed |
| US-6956059-B2 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL, PLC (GB) | 2005-10-18 | — | — | US | claimed |
| US-20040242663-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL, PLC (GB) | 2004-12-02 | — | — | US | claimed |
| EP-1389180-A1 | ANTI-INFLAMMATORY AND IMMUNOMODULATORY AMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | CRODA INTERNATIONAL plc (GB) | 2004-02-18 | — | — | EP | claimed |
| WO-2002094764-A1 | ANTI-INFLAMMATORY AND IMMUNOMODULATORY AMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | CRODA INTERNATIONAL PLC (GB) | 2002-11-28 | — | — | WO | claimed |
| EP-1914223-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL plc (GB) | 2008-04-23 | — | — | EP | disclosed |
| US-6956059-B2 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL, PLC (GB) | 2005-10-18 | — | — | US | disclosed |
| US-20040242663-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL, PLC (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1389180-A1 | ANTI-INFLAMMATORY AND IMMUNOMODULATORY AMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | CRODA INTERNATIONAL plc (GB) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094764-A1 | ANTI-INFLAMMATORY AND IMMUNOMODULATORY AMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | CRODA INTERNATIONAL PLC (GB) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242663-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | ARG1, IL6, IL4I1 | SLC6A5 2993/4885NOD1 87/4885EPHX2 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.