Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507343 | 1.00 | TP53 (0.59) | TP53TSHRPLA2G4BITGB3ITGA2B | |
| SCHEMBL13804958 | 0.95 | LMNA (0.54) | TP53TSHRITGB3ITGA2BLMNA | |
| SCHEMBL27654987 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BLMNA | |
| SCHEMBL27654994 | 0.86 | PPARG (0.54) | ITGB3ITGA2BLMNA | |
| SCHEMBL8953580 | 0.86 | PPARA (0.51) | TP53TSHRPLA2G4BITGB3ITGA2B | |
| SCHEMBL11668908 | 0.85 | TP53 (0.59) | TP53TSHRPLA2G4BITGB3ITGA2B | |
| SCHEMBL7142926 | 0.84 | ITGB3 (0.77) | TP53TSHRPLA2G4BITGB3ITGA2B | |
| SCHEMBL1960616 | 0.84 | ITGB3 (0.77) | TP53TSHRPLA2G4BITGB3ITGA2B | |
| SCHEMBL31193421 | 0.84 | ITGB3 (0.77) | TP53TSHRPLA2G4BITGB3ITGA2B | |
| SCHEMBL1960615 | 0.84 | ITGB3 (0.77) | TP53TSHRPLA2G4BITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514773-A | PARASITICIDES, ANTHELMINTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |