Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL502577 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNA | |
| SCHEMBL967245 | 0.78 | RAB9A (0.72) | NPC1RAB9APKMNAMPTALDH1A1 | |
| SCHEMBL11213715 | 0.78 | RAB9A (0.72) | NPC1RAB9APKMNAMPTALDH1A1 | |
| Ribose (Furanose) SCHEMBL17315074 | 0.77 | F7 (0.56) | ALDH1A1 | |
| Ribose (Furanose) SCHEMBL18185139 | 0.76 | F7 (0.59) | ALDH1A1LMNASMN1; SMN2 | |
| Ribose (Furanose) SCHEMBL338518 | 0.76 | F7 (0.59) | ALDH1A1LMNASMN1; SMN2 | |
| Ribose (Furanose) SCHEMBL14321532 | 0.76 | F7 (0.59) | ALDH1A1LMNASMN1; SMN2 | |
| Methyl Nicotinate SCHEMBL2176622 | 0.76 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1 | |
| Ribose (Furanose) SCHEMBL23111913 | 0.75 | F7 (0.58) | ALDH1A1LMNASMN1; SMN2 | |
| Ribose (Furanose) SCHEMBL18280884 | 0.75 | F7 (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569650-A | C-nucleoside isosters of analogs thereof and pharmaceutical compositions | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-10-29 | — | — | US | disclosed |